SPECT/CT Imaging of hNIS -Expression after Intravenous Delivery of an Oncolytic Adenovirus and (131)I

Oncolytic adenoviruses can be engineered for better tumor selectivity, gene delivery and be armed for imaging and concentrating radionuclides into tumors for synergistic oncolysis. We constructed Ad5/3-hTERT-hNIS where replication is controlled by hTERT-promoter. Ad5/3-hTERT-hNIS expresses hNIS for...

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Detalles Bibliográficos
Autores principales: Rajecki, Maria, Sarparanta, Mirkka, Hakkarainen, Tanja, Tenhunen, Mikko, Diaconu, Iulia, Kuhmonen, Venla, Kairemo, Kalevi, Kanerva, Anna, Airaksinen, Anu J., Hemminki, Akseli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296755/
https://www.ncbi.nlm.nih.gov/pubmed/22412937
http://dx.doi.org/10.1371/journal.pone.0032871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296755/
https://www.ncbi.nlm.nih.gov/pubmed/22412937
http://dx.doi.org/10.1371/journal.pone.0032871

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