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Characterization of the Chromosome 4 Genes That Affect Fluconazole-Induced Disomy Formation in Cryptococcus neoformans

Heteroresistance in Cryptococcus neoformans is an intrinsic adaptive resistance to azoles and the heteroresistant phenotype is associated with disomic chromosomes. Two chromosome 1 (Chr1) genes, ERG11, the fluconazole target, and AFR1, a drug transporter, were reported as major factors in the emerge...

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Detalles Bibliográficos
Autores principales:	Ngamskulrungroj, Popchai, Chang, Yun, Hansen, Bryan, Bugge, Cliff, Fischer, Elizabeth, Kwon-Chung, Kyung J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296764/ https://www.ncbi.nlm.nih.gov/pubmed/22412978 http://dx.doi.org/10.1371/journal.pone.0033022

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