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Simvastatin inhibits sphingosylphosphorylcholine-induced differentiation of human mesenchymal stem cells into smooth muscle cells

Sphingosylphosphorylcholine (SPC) induces differentiation of human adipose tissue-derived mesenchymal stem cells (hASCs) into smooth muscle-like cells expressing α-smooth muscle actin (α-SMA) via transforming growth factor-β1/Smad2- and RhoA/Rho kinase-dependent mechanisms. 3-Hydroxy-3-methylglutary...

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Detalles Bibliográficos
Autores principales:	Kim, Kyung Hye, Kim, Young Mi, Lee, Mi Jeong, Ko, Hyun-Chang, Kim, Moon-Bum, Kim, Jae Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296812/ https://www.ncbi.nlm.nih.gov/pubmed/22127053 http://dx.doi.org/10.3858/emm.2012.44.2.011

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