Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases

Limited neuromuscular input results in muscle weakness in neuromuscular disease either because of a reduction in the density of muscle innervation, the rate of neuromuscular junction activation or the efficiency of synaptic transmission(1). We developed a small molecule fast skeletal troponin activa...

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Detalles Bibliográficos
Autores principales: Russell, Alan J, Hartman, James J, Hinken, Aaron C, Muci, Alexander R, Kawas, Raja, Driscoll, Lena, Godinez, Guillermo, Lee, Kenneth H, Marquez, David, Browne, William F, Chen, Michael M, Clarke, David, Collibee, Scott E, Garard, Marc, Hansen, Richard, Jia, Zhiheng, Lu, Pu-Ping, Rodriguez, Hector, Saikali, Khalil G, Schaletzky, Julia, Vijayakumar, Vipin, Albertus, Daniel L, Claflin, Dennis R, Morgans, David J, Morgan, Bradley P, Malik, Fady I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296825/
https://www.ncbi.nlm.nih.gov/pubmed/22344294
http://dx.doi.org/10.1038/nm.2618

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