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Tetrodotoxin (TTX) as a Therapeutic Agent for Pain
Tetrodotoxin (TTX) is a potent neurotoxin that blocks voltage-gated sodium channels (VGSCs). VGSCs play a critical role in neuronal function under both physiological and pathological conditions. TTX has been extensively used to functionally characterize VGSCs, which can be classified as TTX-sensitiv...
Autores principales: | Nieto, Francisco Rafael, Cobos, Enrique José, Tejada, Miguel Ángel, Sánchez-Fernández, Cristina, González-Cano, Rafael, Cendán, Cruz Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296997/ https://www.ncbi.nlm.nih.gov/pubmed/22412801 http://dx.doi.org/10.3390/md10020281 |
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