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Five New Amicoumacins Isolated from a Marine-Derived Bacterium Bacillus subtilis

Four novel amicoumacins, namely lipoamicoumacins A–D (1–4), and one new bacilosarcin analog (5) were isolated from culture broth of a marine-derived bacterium Bacillus subtilis, together with six known amicoumacins. Their structures were elucidated on the basis of extensive spectroscopic (2D NNR, IR...

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Detalles Bibliográficos
Autores principales: Li, Yongxin, Xu, Ying, Liu, Lingli, Han, Zhuang, Lai, Pok Yui, Guo, Xiangrong, Zhang, Xixiang, Lin, Wenhan, Qian, Pei-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296999/
https://www.ncbi.nlm.nih.gov/pubmed/22412803
http://dx.doi.org/10.3390/md10020319
Descripción
Sumario:Four novel amicoumacins, namely lipoamicoumacins A–D (1–4), and one new bacilosarcin analog (5) were isolated from culture broth of a marine-derived bacterium Bacillus subtilis, together with six known amicoumacins. Their structures were elucidated on the basis of extensive spectroscopic (2D NNR, IR, CD and MS) analysis and in comparison with data in literature.