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Terpenoids from the Octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea)
A new germacrane-type sesquiterpenoid, menelloide E (1), and a new cembrane-type diterpenoid, lobocrassin F (2), were isolated from the octocorals Menella sp. and Lobophytum crassum, respectively. The structures of terpenoids 1 and 2 were determined by spectroscopic and chemical methods and compound...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297006/ https://www.ncbi.nlm.nih.gov/pubmed/22412810 http://dx.doi.org/10.3390/md10020427 |
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| author | Lee, Cheng-Hung Kao, Chia-Ying Kao, Shih-Yao Chang, Chih-Han Su, Jui-Hsin Hwang, Tsong-Long Kuo, Yueh-Hsiung Wen, Zhi-Hong Sung, Ping-Jyun |
| author_facet | Lee, Cheng-Hung Kao, Chia-Ying Kao, Shih-Yao Chang, Chih-Han Su, Jui-Hsin Hwang, Tsong-Long Kuo, Yueh-Hsiung Wen, Zhi-Hong Sung, Ping-Jyun |
| author_sort | Lee, Cheng-Hung |
| collection | PubMed |
| description | A new germacrane-type sesquiterpenoid, menelloide E (1), and a new cembrane-type diterpenoid, lobocrassin F (2), were isolated from the octocorals Menella sp. and Lobophytum crassum, respectively. The structures of terpenoids 1 and 2 were determined by spectroscopic and chemical methods and compound 2 was found to display a significant inhibitory effect on the release of elastase by human neutrophils. |
| format | Online Article Text |
| id | pubmed-3297006 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2012 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-32970062012-03-12 Terpenoids from the Octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea) Lee, Cheng-Hung Kao, Chia-Ying Kao, Shih-Yao Chang, Chih-Han Su, Jui-Hsin Hwang, Tsong-Long Kuo, Yueh-Hsiung Wen, Zhi-Hong Sung, Ping-Jyun Mar Drugs Article A new germacrane-type sesquiterpenoid, menelloide E (1), and a new cembrane-type diterpenoid, lobocrassin F (2), were isolated from the octocorals Menella sp. and Lobophytum crassum, respectively. The structures of terpenoids 1 and 2 were determined by spectroscopic and chemical methods and compound 2 was found to display a significant inhibitory effect on the release of elastase by human neutrophils. MDPI 2012-02-15 /pmc/articles/PMC3297006/ /pubmed/22412810 http://dx.doi.org/10.3390/md10020427 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
| spellingShingle | Article Lee, Cheng-Hung Kao, Chia-Ying Kao, Shih-Yao Chang, Chih-Han Su, Jui-Hsin Hwang, Tsong-Long Kuo, Yueh-Hsiung Wen, Zhi-Hong Sung, Ping-Jyun Terpenoids from the Octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea) |
| title | Terpenoids from the Octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea) |
| title_full | Terpenoids from the Octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea) |
| title_fullStr | Terpenoids from the Octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea) |
| title_full_unstemmed | Terpenoids from the Octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea) |
| title_short | Terpenoids from the Octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea) |
| title_sort | terpenoids from the octocorals menella sp. (plexauridae) and lobophytum crassum (alcyonacea) |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297006/ https://www.ncbi.nlm.nih.gov/pubmed/22412810 http://dx.doi.org/10.3390/md10020427 |
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