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Kinase inhibitors in the treatment of immune-mediated disease
Protein kinases are fundamental components of diverse signaling pathways, including immune cells. Their essential functions have made them effective therapeutic targets. Initially, the expectation was that a high degree of selectivity would be critical; however, with time, the use of “multikinase” i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Faculty of 1000 Ltd
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297200/ https://www.ncbi.nlm.nih.gov/pubmed/22403586 http://dx.doi.org/10.3410/M4-5 |