Nilutamide

The crystal structure of nilutamide [systematic name: 5,5-dimethyl-3-[4-nitro-3-(trifluoro­meth­yl)phen­yl]imidazolidine-2,4-dione], C(12)H(10)F(3)N(3)O(4), was determined at 150 K. The dihedral angle between the mean planes through the imidazoline [maximum deviation = 0.0396 (14) Å] and benzene rin...

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Detalles Bibliográficos
Autores principales: Trasi, Niraj S., Fanwick, Phillip E., Taylor, Lynne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297316/
https://www.ncbi.nlm.nih.gov/pubmed/22412506
http://dx.doi.org/10.1107/S1600536812003728
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author Trasi, Niraj S.
Fanwick, Phillip E.
Taylor, Lynne S.
author_facet Trasi, Niraj S.
Fanwick, Phillip E.
Taylor, Lynne S.
author_sort Trasi, Niraj S.
collection PubMed
description The crystal structure of nilutamide [systematic name: 5,5-dimethyl-3-[4-nitro-3-(trifluoro­meth­yl)phen­yl]imidazolidine-2,4-dione], C(12)H(10)F(3)N(3)O(4), was determined at 150 K. The dihedral angle between the mean planes through the imidazoline [maximum deviation = 0.0396 (14) Å] and benzene rings is 51.49 (5)°. The mol­ecule exhibits inter­molecular hydrogen bonding via N—H⋯O inter­actions, resulting in the formation of chains parallel to the c axis.
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spelling pubmed-32973162012-03-12 Nilutamide Trasi, Niraj S. Fanwick, Phillip E. Taylor, Lynne S. Acta Crystallogr Sect E Struct Rep Online Organic Papers The crystal structure of nilutamide [systematic name: 5,5-dimethyl-3-[4-nitro-3-(trifluoro­meth­yl)phen­yl]imidazolidine-2,4-dione], C(12)H(10)F(3)N(3)O(4), was determined at 150 K. The dihedral angle between the mean planes through the imidazoline [maximum deviation = 0.0396 (14) Å] and benzene rings is 51.49 (5)°. The mol­ecule exhibits inter­molecular hydrogen bonding via N—H⋯O inter­actions, resulting in the formation of chains parallel to the c axis. International Union of Crystallography 2012-02-04 /pmc/articles/PMC3297316/ /pubmed/22412506 http://dx.doi.org/10.1107/S1600536812003728 Text en © Trasi et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Trasi, Niraj S.
Fanwick, Phillip E.
Taylor, Lynne S.
Nilutamide
title Nilutamide
title_full Nilutamide
title_fullStr Nilutamide
title_full_unstemmed Nilutamide
title_short Nilutamide
title_sort nilutamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297316/
https://www.ncbi.nlm.nih.gov/pubmed/22412506
http://dx.doi.org/10.1107/S1600536812003728
work_keys_str_mv AT trasinirajs nilutamide
AT fanwickphillipe nilutamide
AT taylorlynnes nilutamide

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