Significant Association of KIR2DL3-HLA-C1 Combination with Cerebral Malaria and Implications for Co-evolution of KIR and HLA

Cerebral malaria is a major, life-threatening complication of Plasmodium falciparum malaria, and has very high mortality rate. In murine malaria models, natural killer (NK) cell responses have been shown to play a crucial role in the pathogenesis of cerebral malaria. To investigate the role of NK ce...

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Detalles Bibliográficos
Autores principales: Hirayasu, Kouyuki, Ohashi, Jun, Kashiwase, Koichi, Hananantachai, Hathairad, Naka, Izumi, Ogawa, Atsuko, Takanashi, Minoko, Satake, Masahiro, Nakajima, Kazunori, Parham, Peter, Arase, Hisashi, Tokunaga, Katsushi, Patarapotikul, Jintana, Yabe, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297587/
https://www.ncbi.nlm.nih.gov/pubmed/22412373
http://dx.doi.org/10.1371/journal.ppat.1002565

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