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A Disintegrin and Metalloenzyme (ADAM) 17 Activation Is Regulated by α5β1 Integrin in Kidney Mesangial Cells

BACKGROUND: The disintegrin and metalloenzyme ADAM17 participates in numerous inflammatory and proliferative diseases, and its pathophysiological role was implicated in kidney fibrosis, polycystic kidney disease and other chronic kidney diseases. At present, we have little understanding how the enzy...

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Detalles Bibliográficos
Autores principales:	Gooz, Pal, Dang, Yujing, Higashiyama, Shigeki, Twal, Waleed O., Haycraft, Courtney J., Gooz, Monika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297637/ https://www.ncbi.nlm.nih.gov/pubmed/22413019 http://dx.doi.org/10.1371/journal.pone.0033350

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