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Atypical Mechanism of NF-κB activation by TRE17/Ubiquitin-Specific Protease 6 (USP6) oncogene and its requirement in tumorigenesis

The NF-κB transcription factor plays a central role in diverse processes, including inflammation, proliferation and cell survival, and its activity is dysregulated in diseases such as auto-immunity and cancer. We recently identified the TRE17/ubiquitin-specific protease 6 (USP6) oncogene as the firs...

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Detalles Bibliográficos
Autores principales: Pringle, Lashon M., Young, Robert, Quick, Laura, Riquelme, Daisy N., Oliveira, Andre M., May, Michael J., Chou, Margaret M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297677/
https://www.ncbi.nlm.nih.gov/pubmed/22081069
http://dx.doi.org/10.1038/onc.2011.520