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Infectious Diseases Are Analogous With Cancer. Hypothesis And Implications
We propose to disclose first degree analogous features between cancer and infectious diseases and to find out whether these similarities are superficial and negligible, due to the use of the same bodily pathways by the two categories of disease or if they represent significantly parallel characteris...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Ivyspring International Publisher
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297838/ https://www.ncbi.nlm.nih.gov/pubmed/22408684 http://dx.doi.org/10.7150/jca.3977 |
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author | Benharroch, Daniel Osyntsov, Lidia |
author_facet | Benharroch, Daniel Osyntsov, Lidia |
author_sort | Benharroch, Daniel |
collection | PubMed |
description | We propose to disclose first degree analogous features between cancer and infectious diseases and to find out whether these similarities are superficial and negligible, due to the use of the same bodily pathways by the two categories of disease or if they represent significantly parallel characteristics. We have found several primary analogous features, predominantly regarding pathways of spread, but to some extent also concerning the interaction with the immune system. Some of the implications to our hypothesis are probably available in the recent literature, at the experimental or clinical levels. For example endostatin, an angiogenic inhibitor has been used to prevent promotion of metastasis in cancer and to reduce granulomas formation in schistosomiasis. An ECFR antagonist employed to restrain bronchial vessels proliferation in pseudomonas infection, has also been used for the treatment of lung cancer. |
format | Online Article Text |
id | pubmed-3297838 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Ivyspring International Publisher |
record_format | MEDLINE/PubMed |
spelling | pubmed-32978382012-03-09 Infectious Diseases Are Analogous With Cancer. Hypothesis And Implications Benharroch, Daniel Osyntsov, Lidia J Cancer Review We propose to disclose first degree analogous features between cancer and infectious diseases and to find out whether these similarities are superficial and negligible, due to the use of the same bodily pathways by the two categories of disease or if they represent significantly parallel characteristics. We have found several primary analogous features, predominantly regarding pathways of spread, but to some extent also concerning the interaction with the immune system. Some of the implications to our hypothesis are probably available in the recent literature, at the experimental or clinical levels. For example endostatin, an angiogenic inhibitor has been used to prevent promotion of metastasis in cancer and to reduce granulomas formation in schistosomiasis. An ECFR antagonist employed to restrain bronchial vessels proliferation in pseudomonas infection, has also been used for the treatment of lung cancer. Ivyspring International Publisher 2012-03-06 /pmc/articles/PMC3297838/ /pubmed/22408684 http://dx.doi.org/10.7150/jca.3977 Text en © Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited. |
spellingShingle | Review Benharroch, Daniel Osyntsov, Lidia Infectious Diseases Are Analogous With Cancer. Hypothesis And Implications |
title | Infectious Diseases Are Analogous With Cancer. Hypothesis And Implications |
title_full | Infectious Diseases Are Analogous With Cancer. Hypothesis And Implications |
title_fullStr | Infectious Diseases Are Analogous With Cancer. Hypothesis And Implications |
title_full_unstemmed | Infectious Diseases Are Analogous With Cancer. Hypothesis And Implications |
title_short | Infectious Diseases Are Analogous With Cancer. Hypothesis And Implications |
title_sort | infectious diseases are analogous with cancer. hypothesis and implications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297838/ https://www.ncbi.nlm.nih.gov/pubmed/22408684 http://dx.doi.org/10.7150/jca.3977 |
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