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1-(2-Hydroxyethyl)-1′-methyl-4′-(naphthalen-1-yl)-1′′,2′′,3′′,4′′-tetrahydrodispiro[indoline-3,2′-pyrrolidine-3′,2′′-naphthalene]-2,1′′-dione
In the title compound, C(33)H(30)N(2)O(3), the pyrrolidine ring adopts an envelope conformation in which the H atom attached the an ortho-C atom deviates from the plane, whereas the cyclohexanone ring in the tetrahydronaphthalene fused-ring system adopts a sofa conformation. The oxindoline ring...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297867/ https://www.ncbi.nlm.nih.gov/pubmed/22412670 http://dx.doi.org/10.1107/S1600536812006617 |
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author | Selvanayagam, S. Sridhar, B. Saravanan, P. Raghunathan, R. |
author_facet | Selvanayagam, S. Sridhar, B. Saravanan, P. Raghunathan, R. |
author_sort | Selvanayagam, S. |
collection | PubMed |
description | In the title compound, C(33)H(30)N(2)O(3), the pyrrolidine ring adopts an envelope conformation in which the H atom attached the an ortho-C atom deviates from the plane, whereas the cyclohexanone ring in the tetrahydronaphthalene fused-ring system adopts a sofa conformation. The oxindoline ring system is almost perpendicular with respect to the mean plane of the pyrrolidine ring, with a dihedral angle of 89.0 (1)°. Five intramolecular C—H⋯O close contacts are observed. In the crystal, molecules associate via O—H⋯O hydrogen bonds, forming R (2) (2)(14) dimers. In addition, there are weak C—H⋯π interactions. |
format | Online Article Text |
id | pubmed-3297867 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-32978672012-03-12 1-(2-Hydroxyethyl)-1′-methyl-4′-(naphthalen-1-yl)-1′′,2′′,3′′,4′′-tetrahydrodispiro[indoline-3,2′-pyrrolidine-3′,2′′-naphthalene]-2,1′′-dione Selvanayagam, S. Sridhar, B. Saravanan, P. Raghunathan, R. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(33)H(30)N(2)O(3), the pyrrolidine ring adopts an envelope conformation in which the H atom attached the an ortho-C atom deviates from the plane, whereas the cyclohexanone ring in the tetrahydronaphthalene fused-ring system adopts a sofa conformation. The oxindoline ring system is almost perpendicular with respect to the mean plane of the pyrrolidine ring, with a dihedral angle of 89.0 (1)°. Five intramolecular C—H⋯O close contacts are observed. In the crystal, molecules associate via O—H⋯O hydrogen bonds, forming R (2) (2)(14) dimers. In addition, there are weak C—H⋯π interactions. International Union of Crystallography 2012-02-24 /pmc/articles/PMC3297867/ /pubmed/22412670 http://dx.doi.org/10.1107/S1600536812006617 Text en © Selvanayagam et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Selvanayagam, S. Sridhar, B. Saravanan, P. Raghunathan, R. 1-(2-Hydroxyethyl)-1′-methyl-4′-(naphthalen-1-yl)-1′′,2′′,3′′,4′′-tetrahydrodispiro[indoline-3,2′-pyrrolidine-3′,2′′-naphthalene]-2,1′′-dione |
title | 1-(2-Hydroxyethyl)-1′-methyl-4′-(naphthalen-1-yl)-1′′,2′′,3′′,4′′-tetrahydrodispiro[indoline-3,2′-pyrrolidine-3′,2′′-naphthalene]-2,1′′-dione |
title_full | 1-(2-Hydroxyethyl)-1′-methyl-4′-(naphthalen-1-yl)-1′′,2′′,3′′,4′′-tetrahydrodispiro[indoline-3,2′-pyrrolidine-3′,2′′-naphthalene]-2,1′′-dione |
title_fullStr | 1-(2-Hydroxyethyl)-1′-methyl-4′-(naphthalen-1-yl)-1′′,2′′,3′′,4′′-tetrahydrodispiro[indoline-3,2′-pyrrolidine-3′,2′′-naphthalene]-2,1′′-dione |
title_full_unstemmed | 1-(2-Hydroxyethyl)-1′-methyl-4′-(naphthalen-1-yl)-1′′,2′′,3′′,4′′-tetrahydrodispiro[indoline-3,2′-pyrrolidine-3′,2′′-naphthalene]-2,1′′-dione |
title_short | 1-(2-Hydroxyethyl)-1′-methyl-4′-(naphthalen-1-yl)-1′′,2′′,3′′,4′′-tetrahydrodispiro[indoline-3,2′-pyrrolidine-3′,2′′-naphthalene]-2,1′′-dione |
title_sort | 1-(2-hydroxyethyl)-1′-methyl-4′-(naphthalen-1-yl)-1′′,2′′,3′′,4′′-tetrahydrodispiro[indoline-3,2′-pyrrolidine-3′,2′′-naphthalene]-2,1′′-dione |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297867/ https://www.ncbi.nlm.nih.gov/pubmed/22412670 http://dx.doi.org/10.1107/S1600536812006617 |
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