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2-(8-Bromo­imidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethyl­amino-2-hy­droxy­benzyl­idene]acetohydrazide dihydrate

In the title compound, C(20)H(22)BrN(5)O(2)·2H(2)O, the Schiff base mol­ecule exists in an E conformation with respect to the acyclic C=N bond. An S(6) ring motif is formed via an intra­molecular O—H⋯N hydrogen bond. The dihedral angle between the imidazo[1,2-a]pyridine system and the benzene ring i...

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Autores principales: Fun, Hoong-Kun, Loh, Wan-Sin, Shenvi, Seema, Isloor, Arun M., Hegde, Gurumurthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297878/
https://www.ncbi.nlm.nih.gov/pubmed/22412681
http://dx.doi.org/10.1107/S160053681200685X
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author Fun, Hoong-Kun
Loh, Wan-Sin
Shenvi, Seema
Isloor, Arun M.
Hegde, Gurumurthy
author_facet Fun, Hoong-Kun
Loh, Wan-Sin
Shenvi, Seema
Isloor, Arun M.
Hegde, Gurumurthy
author_sort Fun, Hoong-Kun
collection PubMed
description In the title compound, C(20)H(22)BrN(5)O(2)·2H(2)O, the Schiff base mol­ecule exists in an E conformation with respect to the acyclic C=N bond. An S(6) ring motif is formed via an intra­molecular O—H⋯N hydrogen bond. The dihedral angle between the imidazo[1,2-a]pyridine system and the benzene ring is 84.62 (5)°. In the crystal, N—H⋯O, O—H⋯O, O—H⋯N, C—H⋯O and C—H⋯Br hydrogen bonds link the mol­ecules into a three-dimensional network. The crystal packing is further stabilized by C—H⋯π and π–π inter­actions [centroid–centroid distance = 3.5365 (7) Å].
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spelling pubmed-32978782012-03-12 2-(8-Bromo­imidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethyl­amino-2-hy­droxy­benzyl­idene]acetohydrazide dihydrate Fun, Hoong-Kun Loh, Wan-Sin Shenvi, Seema Isloor, Arun M. Hegde, Gurumurthy Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(20)H(22)BrN(5)O(2)·2H(2)O, the Schiff base mol­ecule exists in an E conformation with respect to the acyclic C=N bond. An S(6) ring motif is formed via an intra­molecular O—H⋯N hydrogen bond. The dihedral angle between the imidazo[1,2-a]pyridine system and the benzene ring is 84.62 (5)°. In the crystal, N—H⋯O, O—H⋯O, O—H⋯N, C—H⋯O and C—H⋯Br hydrogen bonds link the mol­ecules into a three-dimensional network. The crystal packing is further stabilized by C—H⋯π and π–π inter­actions [centroid–centroid distance = 3.5365 (7) Å]. International Union of Crystallography 2012-02-24 /pmc/articles/PMC3297878/ /pubmed/22412681 http://dx.doi.org/10.1107/S160053681200685X Text en © Fun et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Fun, Hoong-Kun
Loh, Wan-Sin
Shenvi, Seema
Isloor, Arun M.
Hegde, Gurumurthy
2-(8-Bromo­imidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethyl­amino-2-hy­droxy­benzyl­idene]acetohydrazide dihydrate
title 2-(8-Bromo­imidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethyl­amino-2-hy­droxy­benzyl­idene]acetohydrazide dihydrate
title_full 2-(8-Bromo­imidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethyl­amino-2-hy­droxy­benzyl­idene]acetohydrazide dihydrate
title_fullStr 2-(8-Bromo­imidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethyl­amino-2-hy­droxy­benzyl­idene]acetohydrazide dihydrate
title_full_unstemmed 2-(8-Bromo­imidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethyl­amino-2-hy­droxy­benzyl­idene]acetohydrazide dihydrate
title_short 2-(8-Bromo­imidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethyl­amino-2-hy­droxy­benzyl­idene]acetohydrazide dihydrate
title_sort 2-(8-bromo­imidazo[1,2-a]pyridin-2-yl)-n′-[(e)-4-diethyl­amino-2-hy­droxy­benzyl­idene]acetohydrazide dihydrate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297878/
https://www.ncbi.nlm.nih.gov/pubmed/22412681
http://dx.doi.org/10.1107/S160053681200685X
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