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2-(8-Bromoimidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethylamino-2-hydroxybenzylidene]acetohydrazide dihydrate
In the title compound, C(20)H(22)BrN(5)O(2)·2H(2)O, the Schiff base molecule exists in an E conformation with respect to the acyclic C=N bond. An S(6) ring motif is formed via an intramolecular O—H⋯N hydrogen bond. The dihedral angle between the imidazo[1,2-a]pyridine system and the benzene ring i...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297878/ https://www.ncbi.nlm.nih.gov/pubmed/22412681 http://dx.doi.org/10.1107/S160053681200685X |
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author | Fun, Hoong-Kun Loh, Wan-Sin Shenvi, Seema Isloor, Arun M. Hegde, Gurumurthy |
author_facet | Fun, Hoong-Kun Loh, Wan-Sin Shenvi, Seema Isloor, Arun M. Hegde, Gurumurthy |
author_sort | Fun, Hoong-Kun |
collection | PubMed |
description | In the title compound, C(20)H(22)BrN(5)O(2)·2H(2)O, the Schiff base molecule exists in an E conformation with respect to the acyclic C=N bond. An S(6) ring motif is formed via an intramolecular O—H⋯N hydrogen bond. The dihedral angle between the imidazo[1,2-a]pyridine system and the benzene ring is 84.62 (5)°. In the crystal, N—H⋯O, O—H⋯O, O—H⋯N, C—H⋯O and C—H⋯Br hydrogen bonds link the molecules into a three-dimensional network. The crystal packing is further stabilized by C—H⋯π and π–π interactions [centroid–centroid distance = 3.5365 (7) Å]. |
format | Online Article Text |
id | pubmed-3297878 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-32978782012-03-12 2-(8-Bromoimidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethylamino-2-hydroxybenzylidene]acetohydrazide dihydrate Fun, Hoong-Kun Loh, Wan-Sin Shenvi, Seema Isloor, Arun M. Hegde, Gurumurthy Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(20)H(22)BrN(5)O(2)·2H(2)O, the Schiff base molecule exists in an E conformation with respect to the acyclic C=N bond. An S(6) ring motif is formed via an intramolecular O—H⋯N hydrogen bond. The dihedral angle between the imidazo[1,2-a]pyridine system and the benzene ring is 84.62 (5)°. In the crystal, N—H⋯O, O—H⋯O, O—H⋯N, C—H⋯O and C—H⋯Br hydrogen bonds link the molecules into a three-dimensional network. The crystal packing is further stabilized by C—H⋯π and π–π interactions [centroid–centroid distance = 3.5365 (7) Å]. International Union of Crystallography 2012-02-24 /pmc/articles/PMC3297878/ /pubmed/22412681 http://dx.doi.org/10.1107/S160053681200685X Text en © Fun et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Fun, Hoong-Kun Loh, Wan-Sin Shenvi, Seema Isloor, Arun M. Hegde, Gurumurthy 2-(8-Bromoimidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethylamino-2-hydroxybenzylidene]acetohydrazide dihydrate |
title | 2-(8-Bromoimidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethylamino-2-hydroxybenzylidene]acetohydrazide dihydrate |
title_full | 2-(8-Bromoimidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethylamino-2-hydroxybenzylidene]acetohydrazide dihydrate |
title_fullStr | 2-(8-Bromoimidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethylamino-2-hydroxybenzylidene]acetohydrazide dihydrate |
title_full_unstemmed | 2-(8-Bromoimidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethylamino-2-hydroxybenzylidene]acetohydrazide dihydrate |
title_short | 2-(8-Bromoimidazo[1,2-a]pyridin-2-yl)-N′-[(E)-4-diethylamino-2-hydroxybenzylidene]acetohydrazide dihydrate |
title_sort | 2-(8-bromoimidazo[1,2-a]pyridin-2-yl)-n′-[(e)-4-diethylamino-2-hydroxybenzylidene]acetohydrazide dihydrate |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297878/ https://www.ncbi.nlm.nih.gov/pubmed/22412681 http://dx.doi.org/10.1107/S160053681200685X |
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