7-Benzyl-3-(4-chloro­phen­yl)-2-isobutyl­amino-5,6,7,8-tetra­hydro­pyrido[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(3H)-one

In the title compound, C(26)H(27)ClN(4)OS, the thienopyrimidine fused-ring system is close to coplanar (r.m.s. deviation = 0.0089 Å), with a maximum deviation of 0.0283 (17) Å for the N atom adjacent to the benzene ring. This ring system forms dihedral angles of 83.51 (3) and 88.20 (5)° with the adj...

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Detalles Bibliográficos
Autores principales: Chen, Hong, Liao, Quan-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297883/
https://www.ncbi.nlm.nih.gov/pubmed/22412686
http://dx.doi.org/10.1107/S1600536812007246
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author Chen, Hong
Liao, Quan-Bin
author_facet Chen, Hong
Liao, Quan-Bin
author_sort Chen, Hong
collection PubMed
description In the title compound, C(26)H(27)ClN(4)OS, the thienopyrimidine fused-ring system is close to coplanar (r.m.s. deviation = 0.0089 Å), with a maximum deviation of 0.0283 (17) Å for the N atom adjacent to the benzene ring. This ring system forms dihedral angles of 83.51 (3) and 88.20 (5)° with the adjacent benzyl and phenyl rings, respectively. In the crystal, N—H⋯Cl inter­actions and C—H⋯O hydrogen bonds are observed.
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spelling pubmed-32978832012-03-12 7-Benzyl-3-(4-chloro­phen­yl)-2-isobutyl­amino-5,6,7,8-tetra­hydro­pyrido[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(3H)-one Chen, Hong Liao, Quan-Bin Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(26)H(27)ClN(4)OS, the thienopyrimidine fused-ring system is close to coplanar (r.m.s. deviation = 0.0089 Å), with a maximum deviation of 0.0283 (17) Å for the N atom adjacent to the benzene ring. This ring system forms dihedral angles of 83.51 (3) and 88.20 (5)° with the adjacent benzyl and phenyl rings, respectively. In the crystal, N—H⋯Cl inter­actions and C—H⋯O hydrogen bonds are observed. International Union of Crystallography 2012-02-24 /pmc/articles/PMC3297883/ /pubmed/22412686 http://dx.doi.org/10.1107/S1600536812007246 Text en © Chen and Liao 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Chen, Hong
Liao, Quan-Bin
7-Benzyl-3-(4-chloro­phen­yl)-2-isobutyl­amino-5,6,7,8-tetra­hydro­pyrido[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(3H)-one
title 7-Benzyl-3-(4-chloro­phen­yl)-2-isobutyl­amino-5,6,7,8-tetra­hydro­pyrido[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(3H)-one
title_full 7-Benzyl-3-(4-chloro­phen­yl)-2-isobutyl­amino-5,6,7,8-tetra­hydro­pyrido[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(3H)-one
title_fullStr 7-Benzyl-3-(4-chloro­phen­yl)-2-isobutyl­amino-5,6,7,8-tetra­hydro­pyrido[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(3H)-one
title_full_unstemmed 7-Benzyl-3-(4-chloro­phen­yl)-2-isobutyl­amino-5,6,7,8-tetra­hydro­pyrido[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(3H)-one
title_short 7-Benzyl-3-(4-chloro­phen­yl)-2-isobutyl­amino-5,6,7,8-tetra­hydro­pyrido[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(3H)-one
title_sort 7-benzyl-3-(4-chloro­phen­yl)-2-isobutyl­amino-5,6,7,8-tetra­hydro­pyrido[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(3h)-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297883/
https://www.ncbi.nlm.nih.gov/pubmed/22412686
http://dx.doi.org/10.1107/S1600536812007246
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AT liaoquanbin 7benzyl34chlorophenyl2isobutylamino5678tetrahydropyrido4345thieno23dpyrimidin43hone

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