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8-Benz­yloxy-2-methyl-3-(2-methyl­phenyl)quinazolin-4(3H)-one

In the title methaqua­lone analogue, C(23)H(20)N(2)O(2), the planes of the terminal aromatic rings [dihedral angle between them = 64.52 (7)°] approximately face the fused-ring methyl group and both are twisted with respect to the pyrimidine plane (r.m.s. deviation = 0.028 Å), forming dihedral angles...

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Autores principales: El-Azab, Adel S., Abdel-Aziz, Alaa A.-M., Ng, Seik Weng, Tiekink, Edward R. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297916/
https://www.ncbi.nlm.nih.gov/pubmed/22412719
http://dx.doi.org/10.1107/S1600536812007362
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author El-Azab, Adel S.
Abdel-Aziz, Alaa A.-M.
Ng, Seik Weng
Tiekink, Edward R. T.
author_facet El-Azab, Adel S.
Abdel-Aziz, Alaa A.-M.
Ng, Seik Weng
Tiekink, Edward R. T.
author_sort El-Azab, Adel S.
collection PubMed
description In the title methaqua­lone analogue, C(23)H(20)N(2)O(2), the planes of the terminal aromatic rings [dihedral angle between them = 64.52 (7)°] approximately face the fused-ring methyl group and both are twisted with respect to the pyrimidine plane (r.m.s. deviation = 0.028 Å), forming dihedral angles of 86.9 (3) (with the 2-tolyl ring) and 65.57 (7)°. The 2-tolyl residue is disordered over two almost coplanar but opposite orientations with the major component having a site-occupancy factor of 0.893 (3). The three-dimensional crystal packing is consolidated by C—H⋯O, C—H⋯π and π–π [2-tol­yl–2-tolyl centroid–centroid distance = 3.8099 (6) Å] inter­actions.
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spelling pubmed-32979162012-03-12 8-Benz­yloxy-2-methyl-3-(2-methyl­phenyl)quinazolin-4(3H)-one El-Azab, Adel S. Abdel-Aziz, Alaa A.-M. Ng, Seik Weng Tiekink, Edward R. T. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title methaqua­lone analogue, C(23)H(20)N(2)O(2), the planes of the terminal aromatic rings [dihedral angle between them = 64.52 (7)°] approximately face the fused-ring methyl group and both are twisted with respect to the pyrimidine plane (r.m.s. deviation = 0.028 Å), forming dihedral angles of 86.9 (3) (with the 2-tolyl ring) and 65.57 (7)°. The 2-tolyl residue is disordered over two almost coplanar but opposite orientations with the major component having a site-occupancy factor of 0.893 (3). The three-dimensional crystal packing is consolidated by C—H⋯O, C—H⋯π and π–π [2-tol­yl–2-tolyl centroid–centroid distance = 3.8099 (6) Å] inter­actions. International Union of Crystallography 2012-02-29 /pmc/articles/PMC3297916/ /pubmed/22412719 http://dx.doi.org/10.1107/S1600536812007362 Text en © El-Azab et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
El-Azab, Adel S.
Abdel-Aziz, Alaa A.-M.
Ng, Seik Weng
Tiekink, Edward R. T.
8-Benz­yloxy-2-methyl-3-(2-methyl­phenyl)quinazolin-4(3H)-one
title 8-Benz­yloxy-2-methyl-3-(2-methyl­phenyl)quinazolin-4(3H)-one
title_full 8-Benz­yloxy-2-methyl-3-(2-methyl­phenyl)quinazolin-4(3H)-one
title_fullStr 8-Benz­yloxy-2-methyl-3-(2-methyl­phenyl)quinazolin-4(3H)-one
title_full_unstemmed 8-Benz­yloxy-2-methyl-3-(2-methyl­phenyl)quinazolin-4(3H)-one
title_short 8-Benz­yloxy-2-methyl-3-(2-methyl­phenyl)quinazolin-4(3H)-one
title_sort 8-benz­yloxy-2-methyl-3-(2-methyl­phenyl)quinazolin-4(3h)-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297916/
https://www.ncbi.nlm.nih.gov/pubmed/22412719
http://dx.doi.org/10.1107/S1600536812007362
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