Diethyl 2,6-dimethyl-4-(5-phenyl-1H-pyrazol-4-yl)-1,4-dihydro­pyridine-3,5-dicarboxyl­ate

In the title compound, C(22)H(25)N(3)O(4), the dihydro­pyridine ring adopts a flattened boat conformation. The pyrazole ring makes a dihedral angle of 29.04 (5)° with the benzene ring. The mol­ecular structure is stabilized by an intra­molecular C—H⋯O hydrogen bond which generates an S(9) ring motif...

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Autores principales: Fun, Hoong-Kun, Ooi, Chin Wei, Malladi, Shridhar, Shivananda, K. N., Isloor, Arun M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297939/
https://www.ncbi.nlm.nih.gov/pubmed/22412742
http://dx.doi.org/10.1107/S1600536812008173
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author Fun, Hoong-Kun
Ooi, Chin Wei
Malladi, Shridhar
Shivananda, K. N.
Isloor, Arun M.
author_facet Fun, Hoong-Kun
Ooi, Chin Wei
Malladi, Shridhar
Shivananda, K. N.
Isloor, Arun M.
author_sort Fun, Hoong-Kun
collection PubMed
description In the title compound, C(22)H(25)N(3)O(4), the dihydro­pyridine ring adopts a flattened boat conformation. The pyrazole ring makes a dihedral angle of 29.04 (5)° with the benzene ring. The mol­ecular structure is stabilized by an intra­molecular C—H⋯O hydrogen bond which generates an S(9) ring motif. In the crystal, mol­ecules are linked via N—H⋯O and C—H⋯N hydrogen bonds into a two-dimensional network parallel to the ab plane. The crystal structure is further consolidated by weak C—H⋯π inter­actions.
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spelling pubmed-32979392012-03-12 Diethyl 2,6-dimethyl-4-(5-phenyl-1H-pyrazol-4-yl)-1,4-dihydro­pyridine-3,5-dicarboxyl­ate Fun, Hoong-Kun Ooi, Chin Wei Malladi, Shridhar Shivananda, K. N. Isloor, Arun M. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(22)H(25)N(3)O(4), the dihydro­pyridine ring adopts a flattened boat conformation. The pyrazole ring makes a dihedral angle of 29.04 (5)° with the benzene ring. The mol­ecular structure is stabilized by an intra­molecular C—H⋯O hydrogen bond which generates an S(9) ring motif. In the crystal, mol­ecules are linked via N—H⋯O and C—H⋯N hydrogen bonds into a two-dimensional network parallel to the ab plane. The crystal structure is further consolidated by weak C—H⋯π inter­actions. International Union of Crystallography 2012-02-29 /pmc/articles/PMC3297939/ /pubmed/22412742 http://dx.doi.org/10.1107/S1600536812008173 Text en © Fun et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Fun, Hoong-Kun
Ooi, Chin Wei
Malladi, Shridhar
Shivananda, K. N.
Isloor, Arun M.
Diethyl 2,6-dimethyl-4-(5-phenyl-1H-pyrazol-4-yl)-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title Diethyl 2,6-dimethyl-4-(5-phenyl-1H-pyrazol-4-yl)-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title_full Diethyl 2,6-dimethyl-4-(5-phenyl-1H-pyrazol-4-yl)-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title_fullStr Diethyl 2,6-dimethyl-4-(5-phenyl-1H-pyrazol-4-yl)-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title_full_unstemmed Diethyl 2,6-dimethyl-4-(5-phenyl-1H-pyrazol-4-yl)-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title_short Diethyl 2,6-dimethyl-4-(5-phenyl-1H-pyrazol-4-yl)-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
title_sort diethyl 2,6-dimethyl-4-(5-phenyl-1h-pyrazol-4-yl)-1,4-dihydro­pyridine-3,5-dicarboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297939/
https://www.ncbi.nlm.nih.gov/pubmed/22412742
http://dx.doi.org/10.1107/S1600536812008173
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