A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX

The cellular response to p53 activation varies greatly in a stimulus- and cell type-specific manner. Dissecting the molecular mechanisms defining these cell fate choices will assist the development of effective p53-based cancer therapies and also illuminate fundamental processes by which gene networ...

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Detalles Bibliográficos
Autores principales: Henry, Ryan E, Andrysik, Zdenek, París, Ramiro, Galbraith, Matthew D, Espinosa, Joaquín M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298004/
https://www.ncbi.nlm.nih.gov/pubmed/22246181
http://dx.doi.org/10.1038/emboj.2011.498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298004/
https://www.ncbi.nlm.nih.gov/pubmed/22246181
http://dx.doi.org/10.1038/emboj.2011.498

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