Cargando…
A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX
The cellular response to p53 activation varies greatly in a stimulus- and cell type-specific manner. Dissecting the molecular mechanisms defining these cell fate choices will assist the development of effective p53-based cancer therapies and also illuminate fundamental processes by which gene networ...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
European Molecular Biology Organization
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298004/ https://www.ncbi.nlm.nih.gov/pubmed/22246181 http://dx.doi.org/10.1038/emboj.2011.498 |