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Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression
The glutamatergic system has been implicated in the pathophysiology of depression and the mechanism of action of antidepressants. Leptin, an adipocyte-derived hormone, has antidepressant-like properties. However, the functional role of leptin receptor (Lepr) signaling in glutamatergic neurons remain...
Autores principales: | Guo, M, Lu, Y, Garza, J C, Li, Y, Chua, S C, Zhang, W, Lu, B, Lu, X-Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298113/ https://www.ncbi.nlm.nih.gov/pubmed/22408745 http://dx.doi.org/10.1038/tp.2012.9 |
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