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Ebola Virus Antibody Prevalence in Dogs and Human Risk
During the 2001–2002 outbreak in Gabon, we observed that several dogs were highly exposed to Ebola virus by eating infected dead animals. To examine whether these animals became infected with Ebola virus, we sampled 439 dogs and screened them by Ebola virus–specific immunoglobulin (Ig) G assay, anti...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298261/ https://www.ncbi.nlm.nih.gov/pubmed/15757552 http://dx.doi.org/10.3201/eid1103.040981 |
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author | Allela, Loïs Bourry, Olivier Pouillot, Régis Délicat, André Yaba, Philippe Kumulungui, Brice Rouquet, Pierre Gonzalez, Jean-Paul Leroy, Eric M. |
author_facet | Allela, Loïs Bourry, Olivier Pouillot, Régis Délicat, André Yaba, Philippe Kumulungui, Brice Rouquet, Pierre Gonzalez, Jean-Paul Leroy, Eric M. |
author_sort | Allela, Loïs |
collection | PubMed |
description | During the 2001–2002 outbreak in Gabon, we observed that several dogs were highly exposed to Ebola virus by eating infected dead animals. To examine whether these animals became infected with Ebola virus, we sampled 439 dogs and screened them by Ebola virus–specific immunoglobulin (Ig) G assay, antigen detection, and viral polymerase chain reaction amplification. Seven (8.9%) of 79 samples from the 2 main towns, 15 (15.2%) of 14 the 99 samples from Mekambo, and 40 (25.2%) of 159 samples from villages in the Ebola virus–epidemic area had detectable Ebola virus–IgG, compared to only 2 (2%) of 102 samples from France. Among dogs from villages with both infected animal carcasses and human cases, seroprevalence was 31.8%. A significant positive direct association existed between seroprevalence and the distances to the Ebola virus–epidemic area. This study suggests that dogs can be infected by Ebola virus and that the putative infection is asymptomatic. |
format | Online Article Text |
id | pubmed-3298261 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-32982612012-03-12 Ebola Virus Antibody Prevalence in Dogs and Human Risk Allela, Loïs Bourry, Olivier Pouillot, Régis Délicat, André Yaba, Philippe Kumulungui, Brice Rouquet, Pierre Gonzalez, Jean-Paul Leroy, Eric M. Emerg Infect Dis Research During the 2001–2002 outbreak in Gabon, we observed that several dogs were highly exposed to Ebola virus by eating infected dead animals. To examine whether these animals became infected with Ebola virus, we sampled 439 dogs and screened them by Ebola virus–specific immunoglobulin (Ig) G assay, antigen detection, and viral polymerase chain reaction amplification. Seven (8.9%) of 79 samples from the 2 main towns, 15 (15.2%) of 14 the 99 samples from Mekambo, and 40 (25.2%) of 159 samples from villages in the Ebola virus–epidemic area had detectable Ebola virus–IgG, compared to only 2 (2%) of 102 samples from France. Among dogs from villages with both infected animal carcasses and human cases, seroprevalence was 31.8%. A significant positive direct association existed between seroprevalence and the distances to the Ebola virus–epidemic area. This study suggests that dogs can be infected by Ebola virus and that the putative infection is asymptomatic. Centers for Disease Control and Prevention 2005-03 /pmc/articles/PMC3298261/ /pubmed/15757552 http://dx.doi.org/10.3201/eid1103.040981 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Research Allela, Loïs Bourry, Olivier Pouillot, Régis Délicat, André Yaba, Philippe Kumulungui, Brice Rouquet, Pierre Gonzalez, Jean-Paul Leroy, Eric M. Ebola Virus Antibody Prevalence in Dogs and Human Risk |
title | Ebola Virus Antibody Prevalence in Dogs and Human Risk |
title_full | Ebola Virus Antibody Prevalence in Dogs and Human Risk |
title_fullStr | Ebola Virus Antibody Prevalence in Dogs and Human Risk |
title_full_unstemmed | Ebola Virus Antibody Prevalence in Dogs and Human Risk |
title_short | Ebola Virus Antibody Prevalence in Dogs and Human Risk |
title_sort | ebola virus antibody prevalence in dogs and human risk |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298261/ https://www.ncbi.nlm.nih.gov/pubmed/15757552 http://dx.doi.org/10.3201/eid1103.040981 |
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