A selective and potent CXCR3 antagonist SCH 546738 attenuates the development of autoimmune diseases and delays graft rejection

BACKGROUND: The CXCR3 receptor and its three interferon-inducible ligands (CXCL9, CXCL10 and CXCL11) have been implicated as playing a central role in directing a Th1 inflammatory response. Recent studies strongly support that the CXCR3 receptor is a very attractive therapeutic target for treating a...

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Detalles Bibliográficos
Autores principales: Jenh, Chung-Her, Cox, Mary Ann, Cui, Long, Reich, Eva-Pia, Sullivan, Lee, Chen, Shu-Cheng, Kinsley, David, Qian, Shiguang, Kim, Seong Heon, Rosenblum, Stuart, Kozlowski, Joseph, Fine, Jay S, Zavodny, Paul J, Lundell, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298469/
https://www.ncbi.nlm.nih.gov/pubmed/22233170
http://dx.doi.org/10.1186/10.1186/1471-2172-13-2

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