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Luteolin decreases IGF-II production and downregulates insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells

BACKGROUND: Luteolin is a 3',4',5,7-tetrahydroxyflavone found in various fruits and vegetables. We have shown previously that luteolin reduces HT-29 cell growth by inducing apoptosis and cell cycle arrest. The objective of this study was to examine whether luteolin downregulates the insuli...

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Detalles Bibliográficos
Autores principales:	Lim, Do Young, Cho, Han Jin, Kim, Jongdai, Nho, Chu Won, Lee, Ki Won, Park, Jung Han Yoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298530/ https://www.ncbi.nlm.nih.gov/pubmed/22269172 http://dx.doi.org/10.1186/1471-230X-12-9

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