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Deregulation of apoptosis-related genes is associated with PRV1 overexpression and JAK2 V617F allele burden in Essential Thrombocythemia and Myelofibrosis

BACKGROUND: Essential Thrombocythemia (ET) and Primary Myelofibrosis (PMF) are Chronic Myeloproliferative Neoplasms (MPN) characterized by clonal myeloproliferation/myeloaccumulation without cell maturation impairment. The JAK2 V617F mutation and PRV1 gene overexpression may contribute to MPN physio...

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Detalles Bibliográficos
Autores principales:	Tognon, Raquel, Gasparotto, Elainy PL, Neves, Renata P, Nunes, Natália S, Ferreira, Aline F, Palma, Patrícia VB, Kashima, Simone, Covas, Dimas T, Santana, Mary, Souto, Elizabeth X, Zanichelli, Maria Aparecida, Simões, Belinda P, de Souza, Ana Maria, Castro, Fabíola A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298534/ https://www.ncbi.nlm.nih.gov/pubmed/22300941 http://dx.doi.org/10.1186/1756-8722-5-2

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