Novel polymorphic AluYb8 insertion in the WNK1 gene is associated with blood pressure variation in Europeans

Mutations in WNK1 and WNK4 cause familial hypertension, the Gordon syndrome. WNK1 and WNK4 conserved noncoding regions were targeted to polymorphism screening using DHPLC and DGGE. The scan identified an undescribed polymorphic AluYb8 insertion in WNK1 intron 10. Screening in primates revealed that...

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Detalles Bibliográficos
Autores principales: Putku, Margus, Kepp, Katrin, Org, Elin, Sõber, Siim, Comas, David, Viigimaa, Margus, Veldre, Gudrun, Juhanson, Peeter, Hallast, Pille, Tõnisson, Neeme, Shaw-Hawkins, Sue, Caulfield, Mark J, Khusnutdinova, Elza, Kožich, Viktor, Munroe, Patricia B, Laan, Maris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298642/
https://www.ncbi.nlm.nih.gov/pubmed/21520334
http://dx.doi.org/10.1002/humu.21508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298642/
https://www.ncbi.nlm.nih.gov/pubmed/21520334
http://dx.doi.org/10.1002/humu.21508

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