Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3)

BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) is activated in majority of ovarian tumors and confers resistance to cisplatin treatment in patients with ovarian cancer. We have reported previously that diindolylmethane (DIM) inhibits the growth of ovarian cancer cells. Howeve...

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Detalles Bibliográficos
Autores principales: Kandala, Prabodh K, Srivastava, Sanjay K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298725/
https://www.ncbi.nlm.nih.gov/pubmed/22280969
http://dx.doi.org/10.1186/1741-7015-10-9

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