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CCL2 upregulation triggers hypoxic preconditioning-induced protection from stroke

BACKGROUND: A brief exposure to systemic hypoxia (i.e., hypoxic preconditioning; HPC) prior to transient middle cerebral artery occlusion (tMCAo) reduces infarct volume, blood-brain barrier disruption, and leukocyte migration. CCL2 (MCP-1), typically regarded as a leukocyte-derived pro-inflammatory...

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Detalles Bibliográficos
Autores principales:	Stowe, Ann M, Wacker, Bradley K, Cravens, Petra D, Perfater, Jennifer L, Li, Min K, Hu, Ruilong, Freie, Angela B, Stüve, Olaf, Gidday, Jeffrey M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298779/ https://www.ncbi.nlm.nih.gov/pubmed/22340958 http://dx.doi.org/10.1186/1742-2094-9-33

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