Lactulose: an effective preventive and therapeutic option for ischemic stroke by production of hydrogen

Lactulose, a synthetic sugar not able to be digested and absorbed by human beings, is widely used to treat constipation and hepatic encephalopathy clinically. Through fermentation by the bacteria in the gastrointestinal tract, lactulose can produce considerable amount of hydrogen, which is protectiv...

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Detalles Bibliográficos
Autores principales: Chen, Xiao, Zhai, Xiao, Kang, Zhimin, Sun, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298790/
https://www.ncbi.nlm.nih.gov/pubmed/22309834
http://dx.doi.org/10.1186/2045-9912-2-3
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author Chen, Xiao
Zhai, Xiao
Kang, Zhimin
Sun, Xuejun
author_facet Chen, Xiao
Zhai, Xiao
Kang, Zhimin
Sun, Xuejun
author_sort Chen, Xiao
collection PubMed
description Lactulose, a synthetic sugar not able to be digested and absorbed by human beings, is widely used to treat constipation and hepatic encephalopathy clinically. Through fermentation by the bacteria in the gastrointestinal tract, lactulose can produce considerable amount of hydrogen, which is protective for ischemic stroke as a unique antioxidant. We propose that lactulose can induce the production of endogenous hydrogen that in turn reduces oxidative stress and ameliorate the stroke damage in human beings.
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spelling pubmed-32987902012-03-12 Lactulose: an effective preventive and therapeutic option for ischemic stroke by production of hydrogen Chen, Xiao Zhai, Xiao Kang, Zhimin Sun, Xuejun Med Gas Res Letter to the Editor Lactulose, a synthetic sugar not able to be digested and absorbed by human beings, is widely used to treat constipation and hepatic encephalopathy clinically. Through fermentation by the bacteria in the gastrointestinal tract, lactulose can produce considerable amount of hydrogen, which is protective for ischemic stroke as a unique antioxidant. We propose that lactulose can induce the production of endogenous hydrogen that in turn reduces oxidative stress and ameliorate the stroke damage in human beings. BioMed Central 2012-02-06 /pmc/articles/PMC3298790/ /pubmed/22309834 http://dx.doi.org/10.1186/2045-9912-2-3 Text en Copyright ©2012 Chen et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Letter to the Editor
Chen, Xiao
Zhai, Xiao
Kang, Zhimin
Sun, Xuejun
Lactulose: an effective preventive and therapeutic option for ischemic stroke by production of hydrogen
title Lactulose: an effective preventive and therapeutic option for ischemic stroke by production of hydrogen
title_full Lactulose: an effective preventive and therapeutic option for ischemic stroke by production of hydrogen
title_fullStr Lactulose: an effective preventive and therapeutic option for ischemic stroke by production of hydrogen
title_full_unstemmed Lactulose: an effective preventive and therapeutic option for ischemic stroke by production of hydrogen
title_short Lactulose: an effective preventive and therapeutic option for ischemic stroke by production of hydrogen
title_sort lactulose: an effective preventive and therapeutic option for ischemic stroke by production of hydrogen
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298790/
https://www.ncbi.nlm.nih.gov/pubmed/22309834
http://dx.doi.org/10.1186/2045-9912-2-3
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AT kangzhimin lactuloseaneffectivepreventiveandtherapeuticoptionforischemicstrokebyproductionofhydrogen
AT sunxuejun lactuloseaneffectivepreventiveandtherapeuticoptionforischemicstrokebyproductionofhydrogen

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