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Receptor chimeras demonstrate that the C-terminal domain of the human cytomegalovirus US27 gene product is necessary and sufficient for intracellular receptor localization
BACKGROUND: Human cytomegalovirus (HCMV) is ubiquitous in the population but generally causes only mild or asymptomatic infection except in immune suppressed individuals. HCMV employs numerous strategies for manipulating infected cells, including mimicry of G-protein coupled receptors (GPCRs). The H...
Autores principales: | Stapleton, Lance K, Arnolds, Kathleen L, Lares, Angela P, Devito, Tori M, Spencer, Juliet V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298792/ https://www.ncbi.nlm.nih.gov/pubmed/22339884 http://dx.doi.org/10.1186/1743-422X-9-42 |
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