Cargando…

Ghrelin Protects Spinal Cord Motoneurons Against Chronic Glutamate Excitotoxicity by Inhibiting Microglial Activation

Glutamate excitotoxicity is emerging as a contributor to degeneration of spinal cord motoneurons in amyotrophic lateral sclerosis (ALS). Recently, we have reported that ghrelin protects motoneurons against chronic glutamate excitotoxicity through the activation of extracellular signal-regulated kina...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Sungyoub, Kim, Yumi, Li, Endan, Park, Seungjoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Physiological Society and The Korean Society of Pharmacology 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298825/ https://www.ncbi.nlm.nih.gov/pubmed/22416219 http://dx.doi.org/10.4196/kjpp.2012.16.1.43

Ejemplares similares

Tetanus toxin C-fragment protects against excitotoxic spinal motoneuron degeneration in vivo
por: Netzahualcoyotzi, Citlalli, et al.
Publicado: (2018)

Dopamine protects neurons against glutamate-induced excitotoxicity
por: Vaarmann, A, et al.
Publicado: (2013)

Insulin Protects Cortical Neurons Against Glutamate Excitotoxicity
por: Krasil’nikova, Irina, et al.
Publicado: (2019)

Isoliquiritigenin Protects Neuronal Cells against Glutamate Excitotoxicity
por: Zgodova, Arina, et al.
Publicado: (2022)

Parkin overexpression protects retinal ganglion cells against glutamate excitotoxicity
por: Hu, Xinxin, et al.
Publicado: (2017)

Astaxanthin Protection against Neuronal Excitotoxicity via Glutamate Receptor Inhibition and Improvement of Mitochondrial Function
por: Kandy, Swapna Kannothum, et al.
Publicado: (2022)

An Anthranilate Derivative Inhibits Glutamate Release and Glutamate Excitotoxicity in Rats
por: Lu, Cheng-Wei, et al.
Publicado: (2022)

Protective effects of gonadal hormones on spinal motoneurons following spinal cord injury
por: Sengelaub, Dale R., et al.
Publicado: (2018)

The Microglial-Motoneuron dialogue in ALS
por: APPEL, S.H., et al.
Publicado: (2011)

Pharmacological Sequestration of Mitochondrial Calcium Uptake Protects Neurons Against Glutamate Excitotoxicity
por: Angelova, Plamena R., et al.
Publicado: (2018)

Nicotine protects rat hypoglossal motoneurons from excitotoxic death via downregulation of connexin 36
por: Corsini, Silvia, et al.
Publicado: (2017)

Enrichment of spinal cord cell cultures with motoneurons
Publicado: (1978)

Protection of Pyruvate against Glutamate Excitotoxicity Is Mediated by Regulating DAPK1 Protein Complex
por: Tian, Jingwei, et al.
Publicado: (2014)

CCP1, a Tubulin Deglutamylase, Increases Survival of Rodent Spinal Cord Neurons following Glutamate-Induced Excitotoxicity
por: Ramadan, Yasmin H., et al.
Publicado: (2021)

Ciliary Neurotrophic Factor Protects Striatal Neurons against Excitotoxicity by Enhancing Glial Glutamate Uptake
por: Beurrier, Corinne, et al.
Publicado: (2010)

Mystixin-7 Peptide Protects Ionotropic Glutamatergic Mechanisms against Glutamate-Induced Excitotoxicity In Vitro
por: Mokrushin, Anatoly A.
Publicado: (2016)

Fucoxanthin protects retinal ganglion cells and promotes parkin-mediated mitophagy against glutamate excitotoxicity
por: Lian, Wei, et al.
Publicado: (2023)

Feedback regulation of locomotion by motoneurons in the vertebrate spinal cord
por: Falgairolle, Melanie, et al.
Publicado: (2019)

Silymarin Inhibits Glutamate Release and Prevents against Kainic Acid-Induced Excitotoxic Injury in Rats
por: Lu, Cheng-Wei, et al.
Publicado: (2020)

Excitotoxic glutamate levels drive spinal cord ependymal stem cell proliferation and fate specification through CP-AMPAR signaling
por: Hachem, Laureen D., et al.
Publicado: (2023)

Protection of taurine and granulocyte colony-stimulating factor against excitotoxicity induced by glutamate in primary cortical neurons
por: Pan, Chunliu, et al.
Publicado: (2010)

Metabotropic glutamate receptors inhibit microglial glutamate release
por: McMullan, Stephen M, et al.
Publicado: (2012)

Motoneuronal Spinal Circuits in Degenerative Motoneuron Disease
por: Falgairolle, Mélanie, et al.
Publicado: (2020)

Electrophysiology of the Fetal Spinal Cord : I. Action potentials of the motoneuron
por: Naka, Ken-Ichi
Publicado: (1964)

NDRG2 Protects the Brain from Excitotoxicity by Facilitating Interstitial Glutamate Uptake
por: Yin, Anqi, et al.
Publicado: (2019)

Abnormalities in Glutamate Metabolism and Excitotoxicity in the Retinal Diseases
por: Ishikawa, Makoto
Publicado: (2013)

Genistein Protects against Spinal Cord Injury in Mice by Inhibiting Neuroinflammation via TLR4-Mediated Microglial Polarization
por: Li, Xin-Wu, et al.
Publicado: (2022)

Calpain Inhibition Increases SMN Protein in Spinal Cord Motoneurons and Ameliorates the Spinal Muscular Atrophy Phenotype in Mice
por: de la Fuente, Sandra, et al.
Publicado: (2018)

Ghrelin Inhibits Oligodendrocyte Cell Death by Attenuating Microglial Activation
por: Lee, Jee Youn, et al.
Publicado: (2014)

Amlodipine Improves Spinal Cord Injury Repair by Inhibiting Motoneuronal Apoptosis Through Autophagy Upregulation
por: Huang, Yang, et al.
Publicado: (2022)

Inducing Chronic Excitotoxicity in the Mouse Spinal Cord to Investigate Lower Motor Neuron Degeneration
por: Blizzard, Catherine A., et al.
Publicado: (2016)

Paired corticospinal-motoneuronal stimulation and exercise after spinal cord injury
por: Jo, Hang Jin, et al.
Publicado: (2021)

Neurogenic Effects of Ghrelin on the Hippocampus
por: Kim, Chanyang, et al.
Publicado: (2017)

Retracted: Genistein Protects against Spinal Cord Injury in Mice by Inhibiting Neuroinflammation via TLR4-Mediated Microglial Polarization
por: and Biomechanics, Applied Bionics
Publicado: (2023)

Glutamate Excitotoxicity Inflicts Paranodal Myelin Splitting and Retraction
por: Fu, Yan, et al.
Publicado: (2009)

Insight into Glutamate Excitotoxicity from Synaptic Zinc Homeostasis
por: Takeda, Atsushi
Publicado: (2010)

Protection of cortical cells by equine estrogens against glutamate-induced excitotoxicity is mediated through a calcium independent mechanism
por: Perrella, Joel, et al.
Publicado: (2005)

Magnolol Reduces Glutamate-Induced Neuronal Excitotoxicity and Protects against Permanent Focal Cerebral Ischemia Up to 4 Hours
por: Lee, Wei-Ting, et al.
Publicado: (2012)

A Pulsed Electromagnetic Field Protects against Glutamate-Induced Excitotoxicity by Modulating the Endocannabinoid System in HT22 Cells
por: Li, Xin, et al.
Publicado: (2017)

Neuroprotective potential of Marsilea quadrifolia Linn against monosodium glutamate-induced excitotoxicity in rats
por: Subramanian, Arunkumar, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_uoklol6hj173c0g37fvlr5q0a4