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Rare association of central pontine myelinolysis with infantile tremor syndrome

Central pontine myelinolysis (CPM) is an acute demyelination within the central basis pontis. Though exact mechanism is not known it is seen commonly with rapid correction of hyponatremia and also with pontine ischemia or infarction, demyelinating diseases, pontine neoplasm and different metabolic d...

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Autores principales: Datta, Kalpana, Datta, Supratim, Dutta, Indranil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299072/
https://www.ncbi.nlm.nih.gov/pubmed/22412274
http://dx.doi.org/10.4103/0972-2327.93279
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author Datta, Kalpana
Datta, Supratim
Dutta, Indranil
author_facet Datta, Kalpana
Datta, Supratim
Dutta, Indranil
author_sort Datta, Kalpana
collection PubMed
description Central pontine myelinolysis (CPM) is an acute demyelination within the central basis pontis. Though exact mechanism is not known it is seen commonly with rapid correction of hyponatremia and also with pontine ischemia or infarction, demyelinating diseases, pontine neoplasm and different metabolic diseases. We report a rare association of CPM in a patient of Infantile Tremor Syndrom (ITS). ITS is a syndrome of tremor, mental and physical retardation, pigmentary changes of hair and skin and anemia in malnourished children. Though first reported in Indian subcontinent many identical cases were reported from around the world. Our case is a 15 month old child with generalized tremor, mild hepatosplenomegaly with features of grade II malnutrition including skin and hair changes. All the signs and symtoms of tremor improved after treatment with the World Health Organization (WHO) protocol for protein energy malnutrition (PEM) and administration of propranolol without any side effects.
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spelling pubmed-32990722012-03-12 Rare association of central pontine myelinolysis with infantile tremor syndrome Datta, Kalpana Datta, Supratim Dutta, Indranil Ann Indian Acad Neurol Case Report Central pontine myelinolysis (CPM) is an acute demyelination within the central basis pontis. Though exact mechanism is not known it is seen commonly with rapid correction of hyponatremia and also with pontine ischemia or infarction, demyelinating diseases, pontine neoplasm and different metabolic diseases. We report a rare association of CPM in a patient of Infantile Tremor Syndrom (ITS). ITS is a syndrome of tremor, mental and physical retardation, pigmentary changes of hair and skin and anemia in malnourished children. Though first reported in Indian subcontinent many identical cases were reported from around the world. Our case is a 15 month old child with generalized tremor, mild hepatosplenomegaly with features of grade II malnutrition including skin and hair changes. All the signs and symtoms of tremor improved after treatment with the World Health Organization (WHO) protocol for protein energy malnutrition (PEM) and administration of propranolol without any side effects. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3299072/ /pubmed/22412274 http://dx.doi.org/10.4103/0972-2327.93279 Text en Copyright: © Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Datta, Kalpana
Datta, Supratim
Dutta, Indranil
Rare association of central pontine myelinolysis with infantile tremor syndrome
title Rare association of central pontine myelinolysis with infantile tremor syndrome
title_full Rare association of central pontine myelinolysis with infantile tremor syndrome
title_fullStr Rare association of central pontine myelinolysis with infantile tremor syndrome
title_full_unstemmed Rare association of central pontine myelinolysis with infantile tremor syndrome
title_short Rare association of central pontine myelinolysis with infantile tremor syndrome
title_sort rare association of central pontine myelinolysis with infantile tremor syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299072/
https://www.ncbi.nlm.nih.gov/pubmed/22412274
http://dx.doi.org/10.4103/0972-2327.93279
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