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Prevalence and Immunization Status of Hepatitis B Virus in the HIV Cohort in Fife, Scotland
BACKGROUND: Routes of transmission of hepatitis B virus (HBV)/HIV infections are similar and there is a significant rate of co-infection in patients. A study was recently carried out in NHS Fife, Scotland from February 2007 - February 2008 to estimate the prevalence of HBV/HIV co-infection, occult H...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elmer Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299173/ https://www.ncbi.nlm.nih.gov/pubmed/22457699 http://dx.doi.org/10.4021/jocmr2009.12.1282 |
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author | Hakeem, Lukman Thomson, Grace McCleary, Eleanor Bhattacharyya, Diptendu Banerjee, Indranil |
author_facet | Hakeem, Lukman Thomson, Grace McCleary, Eleanor Bhattacharyya, Diptendu Banerjee, Indranil |
author_sort | Hakeem, Lukman |
collection | PubMed |
description | BACKGROUND: Routes of transmission of hepatitis B virus (HBV)/HIV infections are similar and there is a significant rate of co-infection in patients. A study was recently carried out in NHS Fife, Scotland from February 2007 - February 2008 to estimate the prevalence of HBV/HIV co-infection, occult HBV infection and immunisation status against HBV in a cohort of patients with HIV attending the departments of infectious diseases and genitourinary medicine. METHODS: Case notes were reviewed retrospectively (n = 70). Details on patient demographics, risk category, nadir/current CD4 count, HIV viral load and vaccination history were analysed. HBV markers (HBsAg/anti-HBs/anti-HBc/HBV DNA) and alanine transaminase (ALT) levels were tested prospectively if these tests had not been carried out in the previous 12 months. RESULTS AND CONCLUSION: Prevalence of HBV/HIV co-infection was 5.6% of which 2.8% of patients had occult infection and 22.9% had evidence of previous exposure. Although HBV is preventable by vaccination, only 24.2% of patients had been vaccinated against it. Improvements could therefore be made in the field of prevention with vaccination and monitoring the immune response in this cohort. KEYWORDS: Prevalence; Immunization status; Hepatitis B Virus; HIV |
format | Online Article Text |
id | pubmed-3299173 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Elmer Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-32991732012-03-28 Prevalence and Immunization Status of Hepatitis B Virus in the HIV Cohort in Fife, Scotland Hakeem, Lukman Thomson, Grace McCleary, Eleanor Bhattacharyya, Diptendu Banerjee, Indranil J Clin Med Res Original Article BACKGROUND: Routes of transmission of hepatitis B virus (HBV)/HIV infections are similar and there is a significant rate of co-infection in patients. A study was recently carried out in NHS Fife, Scotland from February 2007 - February 2008 to estimate the prevalence of HBV/HIV co-infection, occult HBV infection and immunisation status against HBV in a cohort of patients with HIV attending the departments of infectious diseases and genitourinary medicine. METHODS: Case notes were reviewed retrospectively (n = 70). Details on patient demographics, risk category, nadir/current CD4 count, HIV viral load and vaccination history were analysed. HBV markers (HBsAg/anti-HBs/anti-HBc/HBV DNA) and alanine transaminase (ALT) levels were tested prospectively if these tests had not been carried out in the previous 12 months. RESULTS AND CONCLUSION: Prevalence of HBV/HIV co-infection was 5.6% of which 2.8% of patients had occult infection and 22.9% had evidence of previous exposure. Although HBV is preventable by vaccination, only 24.2% of patients had been vaccinated against it. Improvements could therefore be made in the field of prevention with vaccination and monitoring the immune response in this cohort. KEYWORDS: Prevalence; Immunization status; Hepatitis B Virus; HIV Elmer Press 2010-02 2010-02-08 /pmc/articles/PMC3299173/ /pubmed/22457699 http://dx.doi.org/10.4021/jocmr2009.12.1282 Text en Copyright 2010, Hakeem et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Hakeem, Lukman Thomson, Grace McCleary, Eleanor Bhattacharyya, Diptendu Banerjee, Indranil Prevalence and Immunization Status of Hepatitis B Virus in the HIV Cohort in Fife, Scotland |
title | Prevalence and Immunization Status of Hepatitis B Virus in the HIV Cohort in Fife, Scotland |
title_full | Prevalence and Immunization Status of Hepatitis B Virus in the HIV Cohort in Fife, Scotland |
title_fullStr | Prevalence and Immunization Status of Hepatitis B Virus in the HIV Cohort in Fife, Scotland |
title_full_unstemmed | Prevalence and Immunization Status of Hepatitis B Virus in the HIV Cohort in Fife, Scotland |
title_short | Prevalence and Immunization Status of Hepatitis B Virus in the HIV Cohort in Fife, Scotland |
title_sort | prevalence and immunization status of hepatitis b virus in the hiv cohort in fife, scotland |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299173/ https://www.ncbi.nlm.nih.gov/pubmed/22457699 http://dx.doi.org/10.4021/jocmr2009.12.1282 |
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