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PI3K/AKT/PTEN Signaling as a Molecular Target in Leukemia Angiogenesis

PI3K/AKT/PTEN pathway is important in the regulation of angiogenesis mediated by vascular endothelial growth factor in many tumors including leukemia. The signaling pathway is activated in leukemia patients as well as leukemia cell lines together with a decrease in the expression of PTEN gene. The m...

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Detalles Bibliográficos
Autores principales:	Okumura, Naoko, Yoshida, Hitomi, Kitagishi, Yasuko, Murakami, Mutsumi, Nishimura, Yuri, Matsuda, Satoru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299269/ https://www.ncbi.nlm.nih.gov/pubmed/22505939 http://dx.doi.org/10.1155/2012/843085

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