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Predictive Models for Maximum Recommended Therapeutic Dose of Antiretroviral Drugs

A novel method for predicting maximum recommended therapeutic dose (MRTD) is presented using quantitative structure property relationships (QSPRs) and artificial neural networks (ANNs). MRTD data of 31 structurally diverse Antiretroviral drugs (ARVs) were collected from FDA MRTD Database or package...

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Detalles Bibliográficos
Autores principales: Branham, Michael Lee, Ross, Edward A., Govender, Thirumala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299291/
https://www.ncbi.nlm.nih.gov/pubmed/22481974
http://dx.doi.org/10.1155/2012/469769

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