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Predictive Models for Maximum Recommended Therapeutic Dose of Antiretroviral Drugs
A novel method for predicting maximum recommended therapeutic dose (MRTD) is presented using quantitative structure property relationships (QSPRs) and artificial neural networks (ANNs). MRTD data of 31 structurally diverse Antiretroviral drugs (ARVs) were collected from FDA MRTD Database or package...
Autores principales: | Branham, Michael Lee, Ross, Edward A., Govender, Thirumala |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299291/ https://www.ncbi.nlm.nih.gov/pubmed/22481974 http://dx.doi.org/10.1155/2012/469769 |
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