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Unilateral Auditory Neuropathy Caused by Cochlear Nerve Deficiency

Objective. To explore possible corelationship between the cochlear nerve deficiency (CND) and unilateral auditory neuropathy (AN). Methods. From a database of 85 patients with unilateral profound sensorineural hearing loss, eight who presented with evoked otoacoustic emissions (EOAEs) or cochlear mi...

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Autores principales: Liu, Cheng, Bu, Xingkuan, Wu, Feiyun, Xing, Guangqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299319/
https://www.ncbi.nlm.nih.gov/pubmed/22518161
http://dx.doi.org/10.1155/2012/914986
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author Liu, Cheng
Bu, Xingkuan
Wu, Feiyun
Xing, Guangqian
author_facet Liu, Cheng
Bu, Xingkuan
Wu, Feiyun
Xing, Guangqian
author_sort Liu, Cheng
collection PubMed
description Objective. To explore possible corelationship between the cochlear nerve deficiency (CND) and unilateral auditory neuropathy (AN). Methods. From a database of 85 patients with unilateral profound sensorineural hearing loss, eight who presented with evoked otoacoustic emissions (EOAEs) or cochlear microphonic (CM) in the affected ear were diagnosed with unilateral AN. Audiological and radiological records in eight patients with unilateral AN were retrospectively reviewed. Results. Eight cases were diagnosed as having unilateral AN caused by CND. Seven had type “A” tympanogram with normal EOAE in both ears. The other patient had unilateral type “B” tympanogram and absent OAE but CM recorded, consistent with middle ear effusion in the affected ear. For all the ears involved in the study, auditory brainstem responses (ABRs) were either absent or responded to the maximum output and the neural responses from the cochlea were not revealed when viewed by means of the oblique sagittal MRI on the internal auditory canal. Conclusion. Cochlear nerve deficiency can be seen by electrophysiological evidence and may be a significant cause of unilateral AN. Inclined sagittal MRI of the internal auditory canal is recommended for the diagnosis of this disorder.
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spelling pubmed-32993192012-04-19 Unilateral Auditory Neuropathy Caused by Cochlear Nerve Deficiency Liu, Cheng Bu, Xingkuan Wu, Feiyun Xing, Guangqian Int J Otolaryngol Clinical Study Objective. To explore possible corelationship between the cochlear nerve deficiency (CND) and unilateral auditory neuropathy (AN). Methods. From a database of 85 patients with unilateral profound sensorineural hearing loss, eight who presented with evoked otoacoustic emissions (EOAEs) or cochlear microphonic (CM) in the affected ear were diagnosed with unilateral AN. Audiological and radiological records in eight patients with unilateral AN were retrospectively reviewed. Results. Eight cases were diagnosed as having unilateral AN caused by CND. Seven had type “A” tympanogram with normal EOAE in both ears. The other patient had unilateral type “B” tympanogram and absent OAE but CM recorded, consistent with middle ear effusion in the affected ear. For all the ears involved in the study, auditory brainstem responses (ABRs) were either absent or responded to the maximum output and the neural responses from the cochlea were not revealed when viewed by means of the oblique sagittal MRI on the internal auditory canal. Conclusion. Cochlear nerve deficiency can be seen by electrophysiological evidence and may be a significant cause of unilateral AN. Inclined sagittal MRI of the internal auditory canal is recommended for the diagnosis of this disorder. Hindawi Publishing Corporation 2012 2012-02-28 /pmc/articles/PMC3299319/ /pubmed/22518161 http://dx.doi.org/10.1155/2012/914986 Text en Copyright © 2012 Cheng Liu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Liu, Cheng
Bu, Xingkuan
Wu, Feiyun
Xing, Guangqian
Unilateral Auditory Neuropathy Caused by Cochlear Nerve Deficiency
title Unilateral Auditory Neuropathy Caused by Cochlear Nerve Deficiency
title_full Unilateral Auditory Neuropathy Caused by Cochlear Nerve Deficiency
title_fullStr Unilateral Auditory Neuropathy Caused by Cochlear Nerve Deficiency
title_full_unstemmed Unilateral Auditory Neuropathy Caused by Cochlear Nerve Deficiency
title_short Unilateral Auditory Neuropathy Caused by Cochlear Nerve Deficiency
title_sort unilateral auditory neuropathy caused by cochlear nerve deficiency
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299319/
https://www.ncbi.nlm.nih.gov/pubmed/22518161
http://dx.doi.org/10.1155/2012/914986
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