Cargando…

Laryngomalacia: Disease Presentation, Spectrum, and Management

Laryngomalacia is the most common cause of stridor in newborns, affecting 45–75% of all infants with congenital stridor. The spectrum of disease presentation, progression, and outcomes is varied. Identifying symptoms and patient factors that influence disease severity helps predict outcomes. Finding...

Descripción completa

Detalles Bibliográficos
Autores principales: Landry, April M., Thompson, Dana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299329/
https://www.ncbi.nlm.nih.gov/pubmed/22518182
http://dx.doi.org/10.1155/2012/753526
_version_ 1782226110004592640
author Landry, April M.
Thompson, Dana M.
author_facet Landry, April M.
Thompson, Dana M.
author_sort Landry, April M.
collection PubMed
description Laryngomalacia is the most common cause of stridor in newborns, affecting 45–75% of all infants with congenital stridor. The spectrum of disease presentation, progression, and outcomes is varied. Identifying symptoms and patient factors that influence disease severity helps predict outcomes. Findings. Infants with stridor who do not have significant feeding-related symptoms can be managed expectantly without intervention. Infants with stridor and feeding-related symptoms benefit from acid suppression treatment. Those with additional symptoms of aspiration, failure to thrive, and consequences of airway obstruction and hypoxia require surgical intervention. The presence of an additional level of airway obstruction worsens symptoms and has a 4.5x risk of requiring surgical intervention, usually supraglottoplasty. The presence of medical comorbidities predicts worse symptoms. Summary. Most with laryngomalacia will have mild-to-moderate symptoms and not require surgical intervention. Those with gastroesophageal reflux and/or laryngopharyngeal reflux have symptom improvement from acid suppression therapy. Those with severe enough disease to require supraglottoplasty will have minimal complications and good outcomes if multiple medical comorbidities are not present. Identifying patient factors that influence disease severity is an important aspect of care provided to infants with laryngomalacia.
format Online
Article
Text
id pubmed-3299329
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-32993292012-04-19 Laryngomalacia: Disease Presentation, Spectrum, and Management Landry, April M. Thompson, Dana M. Int J Pediatr Review Article Laryngomalacia is the most common cause of stridor in newborns, affecting 45–75% of all infants with congenital stridor. The spectrum of disease presentation, progression, and outcomes is varied. Identifying symptoms and patient factors that influence disease severity helps predict outcomes. Findings. Infants with stridor who do not have significant feeding-related symptoms can be managed expectantly without intervention. Infants with stridor and feeding-related symptoms benefit from acid suppression treatment. Those with additional symptoms of aspiration, failure to thrive, and consequences of airway obstruction and hypoxia require surgical intervention. The presence of an additional level of airway obstruction worsens symptoms and has a 4.5x risk of requiring surgical intervention, usually supraglottoplasty. The presence of medical comorbidities predicts worse symptoms. Summary. Most with laryngomalacia will have mild-to-moderate symptoms and not require surgical intervention. Those with gastroesophageal reflux and/or laryngopharyngeal reflux have symptom improvement from acid suppression therapy. Those with severe enough disease to require supraglottoplasty will have minimal complications and good outcomes if multiple medical comorbidities are not present. Identifying patient factors that influence disease severity is an important aspect of care provided to infants with laryngomalacia. Hindawi Publishing Corporation 2012 2012-02-27 /pmc/articles/PMC3299329/ /pubmed/22518182 http://dx.doi.org/10.1155/2012/753526 Text en Copyright © 2012 A. M. Landry and D. M. Thompson. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Landry, April M.
Thompson, Dana M.
Laryngomalacia: Disease Presentation, Spectrum, and Management
title Laryngomalacia: Disease Presentation, Spectrum, and Management
title_full Laryngomalacia: Disease Presentation, Spectrum, and Management
title_fullStr Laryngomalacia: Disease Presentation, Spectrum, and Management
title_full_unstemmed Laryngomalacia: Disease Presentation, Spectrum, and Management
title_short Laryngomalacia: Disease Presentation, Spectrum, and Management
title_sort laryngomalacia: disease presentation, spectrum, and management
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299329/
https://www.ncbi.nlm.nih.gov/pubmed/22518182
http://dx.doi.org/10.1155/2012/753526
work_keys_str_mv AT landryaprilm laryngomalaciadiseasepresentationspectrumandmanagement
AT thompsondanam laryngomalaciadiseasepresentationspectrumandmanagement