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Reversine suppresses oral squamous cell carcinoma via cell cycle arrest and concomitantly apoptosis and autophagy

BACKGROUND: The effective therapies for oral cancer patients of stage III and IV are generally surgical excision and radiation combined with adjuvant chemotherapy using 5-Fu and Cisplatin. However, the five-year survival rate is still less than 30% in Taiwan. Therefore, evaluation of effective drugs...

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Detalles Bibliográficos
Autores principales:	Lee, Ying-Ray, Wu, Wei-Ching, Ji, Wen-Tsai, Chen, Jeff Yi-Fu, Cheng, Ya-Ping, Chiang, Ming-Ko, Chen, Hau-Ren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299600/ https://www.ncbi.nlm.nih.gov/pubmed/22283874 http://dx.doi.org/10.1186/1423-0127-19-9

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