Cooperative Genome-Wide Analysis Shows Increased Homozygosity in Early Onset Parkinson's Disease

Parkinson's disease (PD) occurs in both familial and sporadic forms, and both monogenic and complex genetic factors have been identified. Early onset PD (EOPD) is particularly associated with autosomal recessive (AR) mutations, and three genes, PARK2, PARK7 and PINK1, have been found to carry m...

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Detalles Bibliográficos
Autores principales: Simón-Sánchez, Javier, Kilarski, Laura L., Nalls, Michael A., Martinez, Maria, Schulte, Claudia, Holmans, Peter, Gasser, Thomas, Hardy, John, Singleton, Andrew B., Wood, Nicholas W., Brice, Alexis, Heutink, Peter, Williams, Nigel, Morris, Huw R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299635/
https://www.ncbi.nlm.nih.gov/pubmed/22427796
http://dx.doi.org/10.1371/journal.pone.0028787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299635/
https://www.ncbi.nlm.nih.gov/pubmed/22427796
http://dx.doi.org/10.1371/journal.pone.0028787

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