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Glucuronidated Quercetin Lowers Blood Pressure in Spontaneously Hypertensive Rats via Deconjugation
BACKGROUND: Chronic oral quercetin reduces blood pressure and restores endothelial dysfunction in hypertensive animals. However, quercetin (aglycone) is usually not present in plasma, because it is rapidly metabolized into conjugated, mostly inactive, metabolites. The aim of the study is to analyze...
Autores principales: | Galindo, Pilar, Rodriguez-Gómez, Isabel, González-Manzano, Susana, Dueñas, Montserrat, Jiménez, Rosario, Menéndez, Carmen, Vargas, Félix, Tamargo, Juan, Santos-Buelga, Celestino, Pérez-Vizcaíno, Francisco, Duarte, Juan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299686/ https://www.ncbi.nlm.nih.gov/pubmed/22427863 http://dx.doi.org/10.1371/journal.pone.0032673 |
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