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Nfkb1 Inhibits LPS-Induced IFN-β and IL-12 p40 Production in Macrophages by Distinct Mechanisms

BACKGROUND: Nfkb1-deficient murine macrophages express higher levels of IFN-β and IL-12 p40 following LPS stimulation than control macrophages, but the molecular basis for this phenomenon has not been completely defined. Nfkb1 encodes several gene products including the NF-κB subunit p50 and its pre...

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Detalles Bibliográficos
Autores principales:	Zhao, Xixing, Ross, Erik J., Wang, Yanyan, Horwitz, Bruce H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299705/ https://www.ncbi.nlm.nih.gov/pubmed/22427889 http://dx.doi.org/10.1371/journal.pone.0032811

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