Cargando…
CXCL12 Mediates Trophic Interactions between Endothelial and Tumor Cells in Glioblastoma
Emerging evidence suggests endothelial cells (EC) play a critical role in promoting Glioblastoma multiforme (GBM) cell proliferation and resistance to therapy. The molecular basis for GBM-EC interactions is incompletely understood. We hypothesized that the chemokine CXCL12 and its receptor CXCR4 cou...
Autores principales: | Rao, Shyam, Sengupta, Rajarshi, Choe, Eun Joo, Woerner, B. Mark, Jackson, Erin, Sun, Tao, Leonard, Jeffrey, Piwnica-Worms, David, Rubin, Joshua B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299723/ https://www.ncbi.nlm.nih.gov/pubmed/22427929 http://dx.doi.org/10.1371/journal.pone.0033005 |
Ejemplares similares
-
Novel chemical library screen identifies naturally occurring plant products that specifically disrupt glioblastoma-endothelial cell interactions
por: Sengupta, Rajarshi, et al.
Publicado: (2015) -
PDE7B Is a Novel, Prognostically Significant Mediator of Glioblastoma Growth Whose Expression Is Regulated by Endothelial Cells
por: Brooks, Michael D., et al.
Publicado: (2014) -
Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma
por: Barone, Amy, et al.
Publicado: (2014) -
Cerenkov Radiation Energy Transfer (CRET) Imaging: A Novel Method for Optical Imaging of PET Isotopes in Biological Systems
por: Dothager, Robin S., et al.
Publicado: (2010) -
Casein Kinase 1 Functions as both Penultimate and Ultimate Kinase in Regulating Cdc25A Destruction
por: Honaker, Yuchi, et al.
Publicado: (2010)