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Mechanosensing by the Primary Cilium: Deletion of Kif3A Reduces Bone Formation Due to Loading
Primary cilia, solitary microtubule-based structures that grow from the centriole and extend into the extracellular space, have increasingly been implicated as sensors of a variety of biochemical and biophysical signals. Mutations in primary cilium-related genes have been linked to a number of rare...
Autores principales: | Temiyasathit, Sara, Tang, W. Joyce, Leucht, Philipp, Anderson, Charles T., Monica, Stefanie D., Castillo, Alesha B., Helms, Jill A., Stearns, Tim, Jacobs, Christopher R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299788/ https://www.ncbi.nlm.nih.gov/pubmed/22428034 http://dx.doi.org/10.1371/journal.pone.0033368 |
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