Local Gene Silencing of Monocyte Chemoattractant Protein-1 Prevents Vulnerable Plaque Disruption in Apolipoprotein E-Knockout Mice

Monocyte chemoattractant protein-1 (MCP-1), a CC chemokine (CCL2), has been demonstrated to play important roles in atherosclerosis and becoming an important therapeutic target for atherosclerosis. The present study was undertaken to test the hypothesis that local RNAi of MCP-1 by site-specific deli...

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Detalles Bibliográficos
Autores principales: Liu, Xiao Ling, Zhang, Peng Fei, Ding, Shi Fang, Wang, Yan, Zhang, Mei, Zhao, Yu Xia, Ni, Mei, Zhang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299803/
https://www.ncbi.nlm.nih.gov/pubmed/22428064
http://dx.doi.org/10.1371/journal.pone.0033497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299803/
https://www.ncbi.nlm.nih.gov/pubmed/22428064
http://dx.doi.org/10.1371/journal.pone.0033497

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