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Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia

RATIONALE: Several studies have suggested that modulation of the glutamatergic system via metabotropic glutamate receptors (mGlu) could be a new and efficient way to achieve antipsychotic-like activity. OBJECTIVES: Here, we decided to investigate the possible role of the group III mGlu receptor liga...

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Detalles Bibliográficos
Autores principales:	Wierońska, Joanna M., Stachowicz, Katarzyna, Acher, Francine, Lech, Tomasz, Pilc, Andrzej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2011
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299972/ https://www.ncbi.nlm.nih.gov/pubmed/21952670 http://dx.doi.org/10.1007/s00213-011-2502-2

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