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Native gel electrophoresis of human telomerase distinguishes active complexes with or without dyskerin

Telomeres, the ends of linear chromosomes, safeguard against genome instability. The enzyme responsible for extension of the telomere 3′ terminus is the ribonucleoprotein telomerase. Whereas telomerase activity can be reconstituted in vitro with only the telomerase RNA (hTR) and telomerase reverse t...

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Detalles Bibliográficos
Autores principales:	Gardano, Laura, Holland, Linda, Oulton, Rena, Le Bihan, Thierry, Harrington, Lea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300002/ https://www.ncbi.nlm.nih.gov/pubmed/22187156 http://dx.doi.org/10.1093/nar/gkr1243

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