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A role for insulator elements in the regulation of gene expression response to hypoxia

Hypoxia inducible factor (HIF) up-regulates the transcription of a few hundred genes required for the adaptation to hypoxia. This restricted set of targets is in sharp contrast with the widespread distribution of the HIF binding motif throughout the genome. Here, we investigated the transcriptional...

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Detalles Bibliográficos
Autores principales:	Tiana, Maria, Villar, Diego, Pérez-Guijarro, Eva, Gómez-Maldonado, Laura, Moltó, Eduardo, Fernández-Miñán, Ana, Gómez-Skarmeta, Jose Luis, Montoliu, Lluís, del Peso, Luis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300008/ https://www.ncbi.nlm.nih.gov/pubmed/22067454 http://dx.doi.org/10.1093/nar/gkr842

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