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Chemical structure requirements and cellular targeting of microRNA-122 by peptide nucleic acids anti-miRs

Anti-miRs are oligonucleotide inhibitors complementary to miRNAs that have been used extensively as tools to gain understanding of specific miRNA functions and as potential therapeutics. We showed previously that peptide nucleic acid (PNA) anti-miRs containing a few attached Lys residues were potent...

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Detalles Bibliográficos
Autores principales:	Torres, Adrian G., Fabani, Martin M., Vigorito, Elena, Williams, Donna, Al-Obaidi, Naowras, Wojciechowski, Filip, Hudson, Robert H. E., Seitz, Oliver, Gait, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300011/ https://www.ncbi.nlm.nih.gov/pubmed/22070883 http://dx.doi.org/10.1093/nar/gkr885

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