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Characterization of the kinetic and thermodynamic landscape of RNA folding using a novel application of isothermal titration calorimetry
A novel isothermal titration calorimetry (ITC) method was applied to investigate RNA helical packing driven by the GAAA tetraloop–receptor interaction in magnesium and potassium solutions. Both the kinetics and thermodynamics were obtained in individual ITC experiments, and analysis of the kinetic d...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300012/ https://www.ncbi.nlm.nih.gov/pubmed/22058128 http://dx.doi.org/10.1093/nar/gkr894 |