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Attenuation of loop-receptor interactions with pseudoknot formation

RNA tetraloops can recognize receptors to mediate long-range interactions in stable natural RNAs. In vitro selected GNRA tetraloop/receptor interactions are usually more ‘G/C-rich’ than their ‘A/U-rich’ natural counterparts. They are not as widespread in nature despite comparable biophysical and che...

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Detalles Bibliográficos
Autores principales: Afonin, Kirill A., Lin, Yen-Ping, Calkins, Erin R., Jaeger, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300017/
https://www.ncbi.nlm.nih.gov/pubmed/22080507
http://dx.doi.org/10.1093/nar/gkr926